Systematic RH genotyping and variant identification in French donors of African origin

• Published in: Blood transfusion = Trasfusione del sangue Vol. 12 Suppl 1; no. Suppl 1; pp. s264 - s272
• Main Authors: Kappler-Gratias, Sandrine, Auxerre, Carine, Dubeaux, Isabelle, Beolet, Marylise, Ripaux, Maryline, Le Pennec, Pierre-Yves, Pham, Bach-Nga
• Format: Journal Article
• Language: English
• Published: Italy Edizioni SIMTI - SIMTI Servizi Srl 01.01.2014
• Subjects: Africa - ethnology; African Continental Ancestry Group - genetics; Alleles; Female; France; Gene Frequency; Genetic Linkage; Genotyping Techniques; Haplotypes - genetics; Humans; Immunohaematology; Male; Phenotype; Rh-Hr Blood-Group System - analysis; Rh-Hr Blood-Group System - genetics; France; Africa

RH molecular analysis has enabled the documentation of numerous variants of RHD and RHCE alleles, especially in individuals of African origin. The aim of the present study was to determine the type and frequency of D and/or RhCE variants among blood donors of African origin in France, by performing...