Tumour necrosis factor (TNF)-α-308 gene polymorphism in Indian patients with Takayasu's arteritis - a pilot study

• Published in: Indian journal of medical research (New Delhi, India : 1994) Vol. 137; no. 4; pp. 749 - 752
• Main Authors: Sandhya, P, Danda, Sumita, Danda, Debashish, Lonarkar, Shraddha, Luke, Shana S, Sinha, Shanta, Joseph, George
• Format: Journal Article
• Language: English
• Published: India Medknow Publications & Media Pvt Ltd 01.04.2013
• Subjects: Adolescent; Adult; Alleles; Child; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Humans; India; Japan; Male; Middle Aged; Original; Pilot Projects; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Takayasu Arteritis - genetics; Takayasu Arteritis - pathology; Tumor Necrosis Factor-alpha - genetics; Japan; India

Tumour necrosis factor-alpha (TNF-α)- 308 promoter gene polymorphism has been shown to be associated with several autoimmune disorders and infections such as tuberculosis. There is no study on TNF-α gene polymorphism in Takayasu's arteritis (TA) till date. We aimed to study this polymorphism in...