MicroRNA-205-5p regulates the chemotherapeutic resistance of hepatocellular carcinoma cells by targeting PTEN/JNK/ANXA3 pathway

• Published in: American journal of translational research Vol. 9; no. 9; pp. 4300 - 4307
• Main Authors: Shao, Ping, Qu, Wei-Kun, Wang, Cheng-Ye, Tian, Yu, Ye, Ming-Liang, Sun, De-Guang, Sui, Ji-Dong, Wang, Li-Ming, Fan, Rong, Gao, Zhen-Ming
• Format: Journal Article
• Language: English
• Published: United States e-Century Publishing Corporation 01.01.2017
• Subjects: Original; PTEN; MicroRNA-205; chemotherapeutic resistance; hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a common malignant tumor of the digestive system, and patients with advanced HCC have a poor outlook, partly due to resistance to chemotherapeutic drugs. Previous studies have implicated microRNAs in the regulation of chemoresistance, and we have previously shown th...