Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia - Cenik, Basar; Sephton, Chantelle F; Dewey, Colleen M; Xian, Xunde; Wei, Shuguang; Yu, Kimberley; Niu, Wenze; Coppola, Giovanni; Coughlin, Sarah E; Lee, Suzee E; Dries, Daniel R; Almeida, Sandra; et al. (The Journal of biological chemistry, 2011)
Keywords: Dose-Response Relationship, Drug; Frontotemporal Dementia - drug therapy; Frontotemporal Dementia - metabolism; HEK293 Cells; Histone Deacetylase Inhibitors - pharmacology; Humans; Hydroxamic Acids - pharmacology; Intercellular Signaling Peptides and Proteins - biosynthesis; Neurobiology; Progranulins; Transcription, Genetic - drug effects; Up-Regulation - drug effects; Vorinostat