Controlled cortical impact traumatic brain injury in 3xTg-AD mice causes acute intra-axonal amyloid-β accumulation and independently accelerates the development of tau abnormalities - Tran, Hien T; LaFerla, Frank M; Holtzman, David M; Brody, David L (The Journal of neuroscience, 2011)
Keywords: Alzheimer Disease - etiology; Alzheimer Disease - metabolism; Alzheimer Disease - pathology; Amyloid beta-Peptides - metabolism; Analysis of Variance; Animals; Axons - metabolism; Axons - pathology; Blotting, Western; Brain - metabolism; Brain - pathology; Brain Injuries - complications; Brain Injuries - metabolism; Brain Injuries - pathology; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Mice; Mice, Transgenic - genetics; Neurofibrillary Tangles - metabolism; Neurofibrillary Tangles - pathology; tau Proteins - metabolism; Tauopathies - etiology