Identification of cofilin and LIM-domain-containing protein kinase 1 as novel interaction partners of 14-3-3 zeta

• Published in: Biochemical journal Vol. 369; no. Pt 1; pp. 45 - 54
• Main Authors: Birkenfeld, Jörg, Betz, Heinrich, Roth, Dagmar
• Format: Journal Article
• Language: English
• Published: England 01.01.2003
• Subjects: 14-3-3 Proteins; Actin Depolymerizing Factors; Animals; Base Sequence; Cell Line; COS Cells; DNA Primers; DNA-Binding Proteins - metabolism; Humans; Immunohistochemistry; Lim Kinases; Microfilament Proteins - metabolism; Protein Binding; Protein Kinases; Protein-Serine-Threonine Kinases - metabolism; Rats; Two-Hybrid System Techniques; Tyrosine 3-Monooxygenase - metabolism

Proteins of the 14-3-3 family have been implicated in various physiological processes, and are thought to function as adaptors in various signal transduction pathways. In addition, 14-3-3 proteins may contribute to the reorganization of the actin cytoskeleton by interacting with as yet unidentified...