A successful transplant of embryonic adrenal tissue in a patient with Addison's disease

Well documented reports of the successful transplantation of human adrenal cortical tissue cannot be found in the literature. In 1951 we achieved the successful transplantation of human embryonic adrenal gland (cortical tissue) in a patient with symptomatic adrenal insufficiency (Addison's dise...

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Bibliographic Details
Published inThe Yale journal of biology & medicine Vol. 66; no. 1; pp. 3 - 10
Main Authors Patiño, J F, Fenn, J E
Format Journal Article
LanguageEnglish
Published United States Yale Journal of Biology and Medicine 01.01.1993
Subjects
Addison Disease - history
Addison Disease - surgery
Adrenal Cortex - transplantation
Adult
Fetal Tissue Transplantation - history
History of medicine
History, 20th Century
Humans
Male
Transplantation, Homologous
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Summary:Well documented reports of the successful transplantation of human adrenal cortical tissue cannot be found in the literature. In 1951 we achieved the successful transplantation of human embryonic adrenal gland (cortical tissue) in a patient with symptomatic adrenal insufficiency (Addison's disease), apparently the first instance of histologically documented successful homografting of human adrenal cortex. Because of its historical pertinence, the authors, many years later, herein report on this case, which appeared in the senior author's medical thesis. The report must be viewed in the context of the existing clinical knowledge and technology available 40 years ago.
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ISSN:0044-0086
1551-4056