Molecular Mechanism of Berberine in the Treatment of Calcified Aortic Valve Disease Based on AGE-RAGE Signal Pathway

• Published in: Alternative therapies in health and medicine Vol. 29; no. 8; pp. 42 - 47
• Main Authors: Xiao, Han, Xie, Li, Ma, Yili, Fu, Shilin, Guo, Maoyang, Qian, Dehui
• Format: Journal Article
• Language: English
• Published: Aliso Viejo InnoVision Health Media, Inc 01.11.2023
• Subjects: Age; Atherosclerosis; Calcification; Chemokines; Disease; Kinases; Lipids; Pharmacology; Phosphorylation; Proteins; Signal transduction; Software; Tumor necrosis factor-TNF

Objective * We aimed to explore the molecular mechanism of berberine in the treatment of calcified aortic valve disease through the network pharmacology-molecular docking method. Methods * The targets of berberine and calcified aortic valve disease were retrieved, the interactions between the target...