Awakening responses and diurnal fluctuations of salivary cortisol, DHEA-S and α-amylase in healthy male subjects

• Published in: Neuro-endocrinology letters Vol. 32; no. 4; p. 475
• Main Authors: Ghiciuc, Cristina Mihaela, Cozma-Dima, Corina Lucia, Pasquali, Vittorio, Renzi, Paolo, Simeoni, Simona, Lupusoru, Catalina Elena, Patacchioli, Francesca Romana
• Format: Journal Article
• Language: English
• Published: Sweden 2011
• Subjects: Adult; alpha-Amylases - metabolism; Biomarkers - metabolism; Circadian Rhythm - physiology; Dehydroepiandrosterone Sulfate - metabolism; Humans; Hydrocortisone - metabolism; Hypothalamo-Hypophyseal System - physiology; Male; Pituitary-Adrenal System - physiology; Reference Values; Saliva - metabolism; Wakefulness - physiology; Young Adult

Because the cortisol awakening response (CAR) has received increasing attention as a useful index of adrenocortical activity, the primary objective of this study was to investigate the presence of an awakening response for various salivary biomarkers of adrenocortical activity, including dehydroepia...