Haemolytic anaemia and acute liver failure--the initial manifestations of Wilson's disease

• Published in: Bratislavské lékarské listy Vol. 109; no. 10; p. 434
• Main Authors: Prochazkova, D, Pouchla, S, Mejzlik, V, Kyr, M, Zampachova, V, Hrstkova, H
• Format: Journal Article
• Language: English
• Published: Slovakia 2008
• Subjects: Adolescent; Anemia, Hemolytic - etiology; Female; Hepatolenticular Degeneration - complications; Hepatolenticular Degeneration - diagnosis; Hepatolenticular Degeneration - surgery; Humans; Liver Failure, Acute - etiology; Liver Transplantation

We describe a case of a 16-year-old girl with Wilson disease, which was initially presented as Coombs-negative haemolytic anaemia and acute liver failure. The diagnosis was based on the findings of low ceruloplasmin serum level and high copper levels both in serum and 24-hour urinary excretion. The...