Intensification of Statin Therapy Results in a Rapid Reduction in Atherosclerotic Inflammation: Results of a Multicenter Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography Feasibility Study - TAWAKOL, Ahmed; FAYAD, Zahi A; NUNES, Irene O; BEALS, Chan R; SHANKAR, Sudha S; MOGG, Robin; ALON, Achilles; KLIMAS, Michael T; DANSKY, Hayes; SUBRAMANIAN, Sharath S; ABDELBAKY, Amr; RUDD, James H. F; et al. (Journal of the American College of Cardiology, 2013)
Keywords: Adult; Aged; Aged, 80 and over; Aorta, Thoracic - diagnostic imaging; Aorta, Thoracic - pathology; Atherosclerosis (general aspects, experimental research); Atherosclerosis - diagnostic imaging; Atherosclerosis - drug therapy; Atorvastatin; Biological and medical sciences; Blood and lymphatic vessels; Cardiology. Vascular system; Carotid Arteries - diagnostic imaging; Carotid Arteries - pathology; Double-Blind Method; Feasibility Studies; Female; Fluorodeoxyglucose F18; Heart; Heptanoic Acids - administration & dosage; Heptanoic Acids - therapeutic use; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage; Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use; Inflammation - diagnostic imaging; Inflammation - drug therapy; Male; Medical sciences; Middle Aged; Multimodal Imaging - methods; Plaque, Atherosclerotic - diagnostic imaging; Plaque, Atherosclerotic - drug therapy; Positron-Emission Tomography - methods; Pyrroles - administration & dosage; Pyrroles - therapeutic use; Treatment Outcome; Radionuclide study; Radiodiagnosis; Multicenter study; Cardiovascular disease; Statin derivative; Inflammation; Result; Vascular disease; Reduction; Treatment; Atherosclerosis; Medical imagery; Feasibility; Computerized axial tomography; Circulatory system; Cardiology; Positron emission tomography; Antilipemic agent; Emission tomography; CRP; atherosclerosis; AC; plaque; C-reactive protein; TBR; 2-18F-fluoro-2-deoxy-D-glucose; FDG; atorvastatin; low-density lipoprotein; standardized uptake value; attenuation correction; LDL; SUV; inflammation; statins; PET/CT; target-to-background ratio; positron emission tomography-computed tomographic imaging; most diseased segment; MDS