Pseudoprogression of malignant glioma in Chinese patients receiving concomitant chemoradiotherapy

• Published in: Hong Kong medical journal = Xianggang yi xue za zhi Vol. 18; no. 3; pp. 221 - 225
• Main Authors: Chan, Danny T M, Ng, Rebecca Y T, Siu, Deyond Y W, Tang, Peggy, Kam, Michael K M, Ma, Brigette B Y, Wong, George K C, Ng, Stephanie C P, Pang, Jesse C S, Lau, Claire K Y, Zhu, X L, Ng, H K, Poon, W S
• Format: Journal Article
• Language: English
• Published: China Hong Kong Academy of Medicine 01.06.2012
• Subjects: Adolescent; Adult; Aged; Antineoplastic Agents, Alkylating - adverse effects; Antineoplastic Agents, Alkylating - therapeutic use; Asian Continental Ancestry Group; Biomarkers, Tumor; Brain cancer; Brain Neoplasms - genetics; Brain Neoplasms - therapy; Chemoradiotherapy; Chemotherapy; Disease Progression; DNA Methylation; DNA Modification Methylases - genetics; Glioblastoma - genetics; Glioblastoma - therapy; Glioma; Glioma - genetics; Glioma - therapy; Humans; Magnetic Resonance Imaging; Middle Aged; O-Methylguanine-DNA Methyltransferase - genetics; Patients; Radiation therapy; Treatment Outcome; Young Adult

To investigate the frequency of pseudoprogression of glioblastoma in Chinese patients receiving concomitant chemoradiotherapy and investigate its association with pseudoprogression and tumour molecular marker O(6)-methylguanine-DNA methyltransferase promoter methylation status. Case series with inte...