Clinically significant interstitial lung disease in limited scleroderma: histopathology, clinical features, and survival

• Published in: Chest Vol. 134; no. 3; p. 601
• Main Authors: Fischer, Aryeh, Swigris, Jeffrey J, Groshong, Steve D, Cool, Carlyne D, Sahin, Hakan, Lynch, David A, Curran-Everett, Douglas, Gillis, JoAnn Z, Meehan, Richard T, Brown, Kevin K
• Format: Journal Article
• Language: English
• Published: United States 01.09.2008
• Subjects: Adult; Aged; Biopsy; Cohort Studies; Female; Humans; Kaplan-Meier Estimate; Lung - pathology; Lung Diseases, Interstitial - immunology; Lung Diseases, Interstitial - mortality; Lung Diseases, Interstitial - pathology; Male; Middle Aged; Nuclear Proteins - blood; Retrospective Studies; Scleroderma, Limited - immunology; Scleroderma, Limited - mortality; Scleroderma, Limited - pathology; Tomography, X-Ray Computed

To evaluate the pathologic patterns, clinical features, and survival among subjects with scleroderma (ie, systemic sclerosis [SSc]) and clinically significant interstitial lung disease (ILD) evaluated at an ILD center. Retrospective cohort study of all SSc patients who had been referred for further...