High Resolution Melting Analysis for Rapid Detection of PIK3CA Gene Mutations in Bladder Cancer: A Mutated Target for Cancer Therapy

• Published in: Urology journal Vol. 15; no. 1; p. 26
• Main Authors: Ousati Ashtiani, Zahra, Mehrsai, Abdol Rasoul, Pourmand, Mohammad Reza, Pourmand, Gholam Reza
• Format: Journal Article
• Language: English
• Published: Iran Urology and Nephrology Research Center 01.01.2018
• Subjects: Bladder cancer; Mutation

PIK3CA gene mutations have clinical importance and their presence is associated with therapy response. They are also considered as a molecule for targeted therapy. As regards to their importance, genetic variation within a population as well as among different populations, this study was conducted t...