Collagen XXIV, a vertebrate fibrillar collagen with structural features of invertebrate collagens: selective expression in developing cornea and bone

• Published in: The Journal of biological chemistry Vol. 278; no. 44; pp. 43236 - 43244
• Main Authors: Koch, Manuel, Laub, Friedrich, Zhou, Peihong, Hahn, Rita A, Tanaka, Shizuko, Burgeson, Robert E, Gerecke, Donald R, Ramirez, Francesco, Gordon, Marion K
• Format: Journal Article
• Language: English
• Published: United States 31.10.2003
• Subjects: Amino Acid Motifs; Amino Acid Sequence; Animals; Bone and Bones - embryology; Bone and Bones - metabolism; Cloning, Molecular; Collagen (type XXIV); Collagen - biosynthesis; Collagen - chemistry; Cornea - embryology; Cornea - metabolism; DNA, Complementary - metabolism; Humans; In Situ Hybridization; Mice; Models, Genetic; Molecular Sequence Data; Oligonucleotides, Antisense - metabolism; Peptides - chemistry; Protein Structure, Tertiary; Reverse Transcriptase Polymerase Chain Reaction; RNA - metabolism; RNA, Messenger - metabolism; Sequence Homology, Amino Acid; thrombospodin; Time Factors; Tissue Distribution

Tissue-specific assembly of fibers composed of the major collagen types I and II depends in part on the formation of heterotypic fibrils, using the quantitatively minor collagens V and XI. Here we report the identification of a new fibrillar-like collagen chain that is related to the fibrillar alpha...