Predictive value of HLA class II PCR typing for the outcome of mixed lymphocyte reaction

• Published in: Folia biologica Vol. 44; no. 4; p. 137
• Main Authors: Cukrova, V, Loudova, M, Sramkova, I, Dolezalova, L, Vitek, A
• Format: Journal Article
• Language: English
• Published: Czech Republic 1998
• Subjects: Alleles; Bone Marrow Transplantation - immunology; Evaluation Studies as Topic; Female; Histocompatibility Testing - methods; HLA-A Antigens - genetics; HLA-B Antigens - genetics; HLA-D Antigens - genetics; HLA-DQ Antigens - genetics; HLA-DQ beta-Chains; HLA-DR Antigens - genetics; HLA-DRB1 Chains; Humans; Lymphocyte Culture Test, Mixed; Male; Nuclear Family; Polymerase Chain Reaction - methods; Predictive Value of Tests; Tissue Donors

The use of HLA-DRB1 and -DQB1 polymerase chain reaction-sequence-specific primer (PCR-SSP) typing at different levels of resolution for MLR prediction was assessed in 54 HLA-A and -B matched donor/recipient unrelated pairs and 89 HLA-A and -B identical siblings. Graft-versus-host (GvH) direction one...