T2 relaxation time of the normal-appearing white matter is related to the cognitive status in cerebral small vessel disease

• Published in: Journal of cerebral blood flow and metabolism Vol. 41; no. 7; pp. 1767 - 1777
• Main Authors: Brandhofe, Annemarie, Stratmann, Christoph, Schüre, Jan-Rüdiger, Pilatus, Ulrich, Hattingen, Elke, Deichmann, Ralf, Nöth, Ulrike, Wagner, Marlies, Gracien, René-Maxime, Seiler, Alexander
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.07.2021
• Subjects: Original; quantitative imaging; small vessel disease; white matter; cognitive impairment; microstructure

Previous diffusion tensor imaging (DTI) studies indicate that impaired microstructural integrity of the normal-appearing white matter (NAWM) is related to cognitive impairment in cerebral small vessel disease (SVD). This study aimed to investigate whether quantitative T2 relaxometry is a suitable im...