Immunoreactivity of Brazilian HIV isolates with different V3 motifs

A successful HIV vaccine must elicit immune responses which recognize variants of HIV circulating in the vaccine target population. It is therefore important to understand HIV genetic and antigenic variation in geographic areas where vaccine trials are anticipated.

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Bibliographic Details
Published inMemórias do Instituto Oswaldo Cruz Vol. 91; no. 3; pp. 347 - 348
Main Authors Hendry, R M, Hanson, C V, Bongertz, V, Morgado, M, Duarte, A, Casseb, J, Brigido, L, Sabino, E, Diaz, R, Galvão-Castro, B
Format Journal Article
LanguageEnglish
Published Brazil 01.05.1996
Subjects
AIDS Vaccines
AIDS/HIV
Amino Acid Sequence
Antigenic Variation
Consensus Sequence
HIV - genetics
HIV - immunology
HIV - isolation & purification
human immunodeficiency virus 1
Humans
Neutralization Tests
Peptides - immunology
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Summary:A successful HIV vaccine must elicit immune responses which recognize variants of HIV circulating in the vaccine target population. It is therefore important to understand HIV genetic and antigenic variation in geographic areas where vaccine trials are anticipated.
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ISSN:0074-0276