Nerve granulomas and vasculitis in sarcoid peripheral neuropathy: A clinicopathological study of 11 patients

• Published in: Brain (London, England : 1878) Vol. 125; no. Pt 2; pp. 264 - 275
• Main Authors: SAID, Gérard, LACROIX, Catherine, PLANTE-BORDENEUVE, Violaine, LE PAGE, Laurence, PICO, Fernando, PRESLES, Olivier, SENANT, Jacques, REMY, Pascal, RONDEPIERRE, Philippe, MALLECOURT, Jacques
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.02.2002
• Subjects: Adult; Aged; Aged, 80 and over; Biological and medical sciences; Biopsy; Capillaries - ultrastructure; Electrophysiology; Female; Granuloma - pathology; Guillain-Barre Syndrome; Humans; Male; Medical sciences; Middle Aged; Muscle, Skeletal - pathology; Muscle, Skeletal - physiopathology; Muscle, Skeletal - ultrastructure; Neural Conduction; Peripheral Nerves - pathology; Peripheral Nerves - physiopathology; Peripheral Nerves - ultrastructure; Peripheral Nervous System Diseases - etiology; Peripheral Nervous System Diseases - pathology; Peripheral Nervous System Diseases - physiopathology; Retrospective Studies; Sarcoidosis - pathology; Sarcoidosis - physiopathology; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; Vasculitis - pathology; Human; Granuloma; Nervous system diseases; Necrotizing vasculitis; Sarcoidosis; Cardiovascular disease; Peripheral neuropathy; Vascular disease; Electrodiagnosis; Pathology; Nerve conduction; Systemic disease; Adult; Complication; Motor nerve; Peripheral nerve disease; Diagnosis

Peripheral neuropathy is a rare, yet treatable manifestation of sarcoidosis, a multisystem disorder characterized by the presence of non-caseating granulomas that are seldom found in nerve biopsy specimens. In order to learn more about the subject, we reviewed our clinical and pathological findings...