The Dual Impact of Obesity and Diabetes on Heart Failure Readmissions: Results from the Congestive Heart Failure Registry at Harlem Hospital Center

This study aimed to investigate the obesity paradox in patients with congestive heart failure (CHF) at Harlem Hospital Center (HHC), examine the role of diabetes in CHF readmissions, and explore the combined impact of obesity and diabetes on readmission rates. A retrospective chart review was conduc...

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Published inMedical principles and practice p. 1
Main Authors Magdits, Mariel, AlShammari, Asmaa, Majdalani, Rosemarie, Devarajan, Sriraman, Raiszadeh, Farbod
Format Journal Article
LanguageEnglish
Published Switzerland S. Karger AG 30.05.2025
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ISSN1011-7571
1423-0151
DOI10.1159/000546681

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Abstract This study aimed to investigate the obesity paradox in patients with congestive heart failure (CHF) at Harlem Hospital Center (HHC), examine the role of diabetes in CHF readmissions, and explore the combined impact of obesity and diabetes on readmission rates. A retrospective chart review was conducted on 390 patients from HHCs CHF registry (January 2019-December 2021). CHF admissions and 30-day readmissions were analyzed, focusing on obesity, diabetes, and their interplay. Preliminary analyses revealed a correlation between obesity and reduced 30-day readmission rates. Diabetes alone did not significantly influence readmissions; however, patients with both obesity and diabetes had higher readmission rates than those with obesity alone. However, after adjusting for confounders, none of the observed associations remained statistically significant, highlighting the complexity of interpreting the obesity paradox in this population. These findings suggest that the obesity paradox may exist but is attenuated by the presence of diabetes. Further research is needed to elucidate these relationships and their implications for managing CHF in obese diabetic patients.
AbstractList This study aimed to investigate the obesity paradox in patients with congestive heart failure (CHF) at Harlem Hospital Center (HHC), examine the role of diabetes in CHF readmissions, and explore the combined impact of obesity and diabetes on readmission rates. A retrospective chart review was conducted on 390 patients from HHCs CHF registry (January 2019-December 2021). CHF admissions and 30-day readmissions were analyzed, focusing on obesity, diabetes, and their interplay. Preliminary analyses revealed a correlation between obesity and reduced 30-day readmission rates. Diabetes alone did not significantly influence readmissions; however, patients with both obesity and diabetes had higher readmission rates than those with obesity alone. However, after adjusting for confounders, none of the observed associations remained statistically significant, highlighting the complexity of interpreting the obesity paradox in this population. These findings suggest that the obesity paradox may exist but is attenuated by the presence of diabetes. Further research is needed to elucidate these relationships and their implications for managing CHF in obese diabetic patients.
Author AlShammari, Asmaa
Majdalani, Rosemarie
Devarajan, Sriraman
Raiszadeh, Farbod
Magdits, Mariel
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  fullname: Raiszadeh, Farbod
  organization: Harlem Hospital Center, Health + Hospitals, Vagelos College of Physicians and Surgeons, Columbia University, New York, New York, USA
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Keywords Obesity paradox
Obesity
Congestive heart failure
Diabetes
Hospital readmissions
Language English
License 2025 The Author(s). Published by S. Karger AG, Basel.
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Title The Dual Impact of Obesity and Diabetes on Heart Failure Readmissions: Results from the Congestive Heart Failure Registry at Harlem Hospital Center
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