Role of leukotrienes in the pathogenesis of dysmenorrhea in adolescent girls

• Published in: Turkish journal of pediatrics Vol. 50; no. 6; pp. 521 - 525
• Main Authors: Kiliç, Ilke, Oksüz-Kanbur, Nuray, Derman, Orhan, Aksu, Tarik, Uysal-Soyer, Ozge, Kalayci, Omer, Kutluk, Tezer
• Format: Journal Article
• Language: English
• Published: Turkey Hacettepe University Faculty of Medicine 01.11.2008
• Subjects: Adolescent; Analysis of Variance; Case-Control Studies; Dysmenorrhea - blood; Dysmenorrhea - urine; Female; Humans; Leukotriene E4 - urine; Progesterone - blood; Prostaglandins - blood

Although dysmenorrhea is a leading cause of gynecologic complaints among adolescents, its pathogenesis is incompletely understood. The purpose of this study was to determine the role of prostaglandins and leukotrienes in the pathogenesis of dysmenorrhea. Twenty patients with dysmenorrhea aged 16.2+/...