Prenatal diagnosis of supernumerary ring chromosome 1: case report and review of the literature

• Published in: Genetic counseling Vol. 18; no. 2; pp. 233 - 241
• Main Authors: Wray, A M, Dennis, T R, Ghidini, A, Gorman, B, Haddad, B R, Meck, J M
• Format: Journal Article
• Language: English
• Published: Switzerland Éditions Médecine et Hygiène 01.01.2007
• Subjects: Abortion, Eugenic; Adult; Amniocentesis; Chromosome Aberrations; Chromosomes, Human, Pair 1 - genetics; Female; Genetic Counseling; Genetic Markers - genetics; Genetic Testing; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Male; Maternal Age; Pregnancy; Ring Chromosomes

A supernumerary ring chromosome was found on amniocentesis performed for advanced maternal age. A review of the literature found 34 reports of supernumerary ring chromosome I which are compared to our case.