Decreased hepatic nitric oxide synthesis during liver surgery

• Published in: Hepato-gastroenterology Vol. 46; no. 27; p. 1917
• Main Authors: Ueda, T, Sakabe, T, Oka, M, Maeda, Y, Nishida, M, Murakami, F, Maekawa, T
• Format: Journal Article
• Language: English
• Published: Greece 01.05.1999
• Subjects: Adult; Aged; Arginine - blood; Carcinoma, Hepatocellular - blood; Carcinoma, Hepatocellular - surgery; Citrulline - blood; Female; Hepatectomy; Humans; Liver Function Tests; Liver Neoplasms - blood; Liver Neoplasms - secondary; Liver Neoplasms - surgery; Male; Middle Aged; Nitrates - blood; Nitric Oxide - blood; Nitrites - blood; Reference Values

Liver cells can produce nitric oxide from L-arginine through the action of nitric oxide synthase, but local changes in the concentrations of nitric oxide-related metabolites during liver surgery are not well characterized. We investigated such changes during and after liver surgery. We determined ni...