Relationship between the levels of purine salvage pathway enzymes and clinical/biological aggressiveness of human colon carcinoma

• Published in: Cancer biochemistry biophysics Vol. 14; no. 1; p. 57
• Main Authors: Sanfilippo, O, Camici, M, Tozzi, M G, Turriani, M, Faranda, A, Ipata, P L, Silvestrini, R
• Format: Journal Article
• Language: English
• Published: England 01.04.1994
• Subjects: 5'-Nucleotidase - metabolism; Adenosine Deaminase - metabolism; Alkaline Phosphatase - metabolism; Colonic Neoplasms - enzymology; Colonic Neoplasms - metabolism; Colonic Neoplasms - pathology; Humans; Hypoxanthine Phosphoribosyltransferase - metabolism; Intestinal Mucosa - enzymology; Liver Neoplasms - enzymology; Liver Neoplasms - secondary; Neoplasm Invasiveness - physiopathology; Purine-Nucleoside Phosphorylase - metabolism; Purines - metabolism

A large series of samples obtained after surgical resection of intestinal mucosa of patients affected by intestinal carcinoma was examined in order to define possible relationships between levels of enzymes involved in the purine salvage pathway and clinical/biological parameters of aggressiveness a...