First‐in‐man study to investigate safety, pharmacokinetics and exploratory pharmacodynamics of HTL0018318, a novel M1‐receptor partial agonist for the treatment of dementias - Bakker, Charlotte; Tasker, Tim; Liptrot, Jan; Hart, Ellen P.; Klaassen, Erica S.; Prins, Samantha; Doef, Thalia F.; Brown, Giles A.; Brown, Alastair; Congreve, Miles; Weir, Malcolm; Marshall, Fiona H.; et al. (British journal of clinical pharmacology, 2021)
Keywords: Alzheimer's disease; healthy subjects; muscarinic; Original; pharmacokinetics; safety