Salmonellosis: lessons drawn from a germ-free pig model

The germ-free pig model is shown to be useful for studying salmonellosis. The immune status of germ-free and infected gnotobiotic piglets is described. The regulatory role of cytokine is discussed and compared with our experimental findings.

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Bibliographic Details
Published inFolia microbiologica Vol. 43; no. 6; pp. 697 - 701
Main Authors Trebichavský, I, Schulze, J, Dlabac, V, Cukrowska, B, Tlaskalová-Hogenová, H, Reháková, Z
Format Journal Article
LanguageEnglish
Published United States Springer Nature B.V 01.01.1998
Subjects
Animals
Antibodies, Bacterial - blood
B-Lymphocytes - microbiology
Cytokines
Disease Models, Animal
Germfree
Gnotobiotic
Immune status
Immunoglobulin A - blood
Immunoglobulin G - blood
Immunoglobulin M - blood
Immunology
Interferon-gamma - blood
Microbiology
Salmonella
Salmonella Infections, Animal - immunology
Salmonella Infections, Animal - microbiology
Salmonella typhimurium - immunology
Salmonellosis
Salmonidae
Specific Pathogen-Free Organisms
Swine
Tumor Necrosis Factor-alpha - metabolism
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Summary:The germ-free pig model is shown to be useful for studying salmonellosis. The immune status of germ-free and infected gnotobiotic piglets is described. The regulatory role of cytokine is discussed and compared with our experimental findings.
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ISSN:0015-5632
1874-9356
DOI:10.1007/BF02816393