Non‐genomic inhibition of human P2X7 purinoceptor by 17β‐oestradiol

• Published in: The Journal of physiology Vol. 508; no. 3; pp. 659 - 666
• Main Authors: Cario‐Toumaniantz, Chrystelle, Loirand, Gervaise, Ferrier, Laurent, Pacaud, Pierre
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 01.05.1998; Blackwell Science Inc
• Subjects: Rapid Report

1 Effects of oestrogen on the current evoked by ATP and benzoylbenzoyl ATP (BzATP) in CV‐1 monkey kidney cells transformed by SV 40 (COS cells) expressing the human P2X7 (hP2X7) purinoceptor were studied using standard patch‐clamp techniques. 2 17β‐Oestradiol rapidly and reversibly inhibited the who...