Laparoscopy versus open surgery for adnexal masses in pregnancy: a meta-analytic review

• Published in: Archives of gynecology and obstetrics Vol. 299; no. 3; pp. 625 - 634
• Main Authors: Ye, Piaopiao, Zhao, Na, Shu, Jing, Shen, Heping, Wang, Yanpeng, Chen, Lifeng, Yan, Xiaojian
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.03.2019; Springer Nature B.V
• Subjects: Endocrinology; Gynecology; Human Genetics; Laparoscopy; Medicine; Medicine & Public Health; Meta-analysis; Obstetrics/Perinatology/Midwifery; Pregnancy; Review; Surgery; Pregnancy; Laparoscopy; Adnexal masses; Open surgery; Meta-analysis
• DOI: 10.1007/s00404-018-05039-y
• ISSN: 0932-0067; 1432-0711

Purpose The objective of this meta-analysis is to investigate and compare the pregnancy outcomes of laparoscopy and open surgery in the treatment of ovarian tumors during pregnancy. Methods Search was conducted using MEDLINE, EMBASE, and Cochrane Databases from January 1990 to November 2018. A broad search strategy was used to identify studies comparing laparoscopy and open surgery in pregnancy. Inclusion criteria included comparative studies with the quantitative outcome data on gravida. Two authors independently reviewed and assessed for the quality of included studies according to the Newcastle–Ottawa Scale. Data were extracted for fetal loss, preterm delivery, duration of surgery, blood loss and length of hospital stay. Results Nine retrospective trials were identified involving 985 patients. No statistical significance was found in fetal loss between laparoscopy and open surgery ( P value = 0.334). The pooled estimate for preterm labor statistically significantly decreased for laparoscopy group ( P value = 0.014). Reduced operative blood loss was found in laparoscopy group by 83.81 ml ( P value = 0.015). Duration of operation may be longer in the laparoscopy group, but without statistical significance ( P value = 0.346). Length of hospital stay was shorter in the laparoscopy group with reduction of 1.95 days ( P value < 0.001). Conclusions The available low-grade evidence suggests that laparoscopic surgery might be a feasible alternative for pregnant women with adnexal masses.