Oropouche virus infection induces ROS production and oxidative stress in liver and spleen of mice

• Published in: Journal of general virology Vol. 104; no. 5
• Main Authors: da Silva Menegatto, Marília Bueno, Ferraz, Ariane Coelho, Lima, Rafaela Lameira Souza, Almeida, Letícia Trindade, de Brito, Rory Cristiane Fortes, Reis, Alexandre Barbosa, Carneiro, Cláudia Martins, de Lima, Wanderson Geraldo, de Mello Silva, Breno, de Magalhães, José Carlos, Magalhães, Cintia Lopes de Brito
• Format: Journal Article
• Language: English
• Published: England 01.05.2023
• Subjects: Animals; Bunyaviridae Infections; Liver - pathology; Mice; Oxidative Stress; Reactive Oxygen Species; Spleen - pathology; oropouche virus; antioxidant; phatogenesis; oxidative stress; reactive oxygen species

Oropouche virus (OROV) is the aetiological agent of Oropouche fever, the symptoms of which are common to most arboviruses, such as fever, headache, malaise, nausea and vomiting. More than half a million people have been infected with OROV since its isolation in 1955. Although Oropouche fever is clas...