Thrombotic sinusoiditis and local diffuse intrasinusoidal coagulation in the liver of subjects affected by COVID-19: the evidence from histology and scanning electron microscopy

• Published in: European review for medical and pharmacological sciences Vol. 25; no. 19; p. 5904
• Main Authors: Fanni, D, Cerrone, G, Saba, L, Demontis, R, Congiu, T, Piras, M, Gerosa, C, Suri, J S, Coni, P, Caddori, A, Piga, M, Mancosu, G, Barcellona, D, Ravarino, A, Chighine, A, Cau, F, Scano, A, Balestrieri, A, Coghe, F, Orrù, G, Van Eyken, P, La Nasa, G, D'Aloia, E, Marongiu, F, Faa, G
• Format: Journal Article
• Language: English
• Published: Italy 01.10.2021
• Subjects: Aged; Autopsy; Biopsy; Blood Coagulation Disorders - pathology; COVID-19 - pathology; Erythrocytes - pathology; Fibrin; Hepatocytes - pathology; Humans; Liver - pathology; Liver Diseases - pathology; Male; Microscopy, Electron, Scanning; Middle Aged; Thrombosis - complications; Thrombosis - pathology; Young Adult

Liver injury has been reported in patients with COVID-19. This condition is characterized by severe outcome and could be related with the ability of SARS-CoV-2 to activate cytotoxic T cells. The purpose of this study is to show the histological and scanning electron microscopy features of liver invo...