Response of chronic gingivitis to hygiene therapy and experimental gingivitis. Clinical, microbiological and metabonomic changes

• Published in: American journal of dentistry Vol. 28; no. 5; p. 273
• Main Authors: Klukowska, Malgorzata, Goyal, C Ram, Khambe, Deepa, Cannon, Michael, Miner, Melanie, Gurich, Nataliya, Circello, Ben, Huggins, Tom, Barker, Matthew L, Furnish, Carrie, Conde, Erinn, Hoke, Phyllis, Haught, Chris, Xie, Sancai, White, Donald J
• Format: Journal Article
• Language: English
• Published: United States 01.10.2015
• Subjects: Adult; Butyric Acid - analysis; Chronic Disease; Cohort Studies; Dental Devices, Home Care; Dental Plaque - microbiology; Dental Prophylaxis - methods; Female; Gingival Hemorrhage - metabolism; Gingival Hemorrhage - microbiology; Gingival Hemorrhage - therapy; Gingivitis - metabolism; Gingivitis - microbiology; Gingivitis - therapy; Gram-Negative Bacteria - classification; Gram-Positive Bacteria - classification; Humans; Magnetic Resonance Spectroscopy; Male; Metabolome; Middle Aged; Oral Hygiene; Periodontal Index; Propionates - analysis; Real-Time Polymerase Chain Reaction; Recurrence; Saliva - metabolism; Toothbrushing - methods

To compare the clinical, microbiological and metabonomic profiles of subjects with high and low levels of chronic gingival bleeding during a controlled oral hygiene regimen intervention including sequential phases of rigorous therapeutic oral hygiene followed by experimental gingivitis (EG). Two coh...