Research of the effect of miR-663 on the proliferation of prostate cancer cells, and the correlations of miR-663 with pathological grade and clinical stage

• Published in: Journal of B.U. ON. Vol. 22; no. 4; p. 1011
• Main Authors: Wang, Shifeng, Liu, Jingsong, Li, Changming, Yang, Xue
• Format: Journal Article
• Language: English
• Published: Greece 01.07.2017
• Subjects: Case-Control Studies; Cell Line, Tumor; Cell Proliferation - genetics; Disease Progression; Disease-Free Survival; Humans; Kaplan-Meier Estimate; Male; MicroRNAs - genetics; Neoplasm Metastasis - genetics; Neoplasm Metastasis - pathology; Neoplasm Staging; PC-3 Cells; Prognosis; Prostate - pathology; Prostatic Neoplasms - genetics; Prostatic Neoplasms - pathology

To investigate the effect of miR-663 on the proliferation of prostate cancer (PCa) cells, and the correlations of miR-663 with pathological grade and clinical stage. PC-3 and DU-145 PCa cell lines were transfected by artificially synthesized miR-663 and its antisense plasmid, and cell proliferation...