Aspects of the innate immune response to intramammary Staphylococcus aureus infections in cattle

• Published in: Revista argentina de microbiología Vol. 46; no. 4; pp. 363 - 375
• Main Authors: Pereyra, Elizabet A L, Dallard, Bibiana E, Calvinho, Luis F
• Format: Journal Article
• Language: Spanish
• Published: Argentina 01.10.2014
• Subjects: Animals; Cattle; Cytokines - physiology; Female; Immunity, Innate; Mastitis, Bovine - immunology; Mastitis, Bovine - microbiology; Staphylococcal Infections - immunology; Staphylococcal Infections - veterinary; Respuesta inmune innata; Bovine mastitis; Innate immune response; Staphylococcus aureus; Mastitis bovina
• DOI: 10.1016/S0325-7541(14)70096-3
• ISSN: 0325-7541

Staphylococcus aureus is the pathogen most frequently isolated from bovine mastitis worldwide, causing chronic intramammary infections that limit profitable dairying. The objective of this article is to characterize the mechanisms involved in S. aureus mammary gland infections considering two different aspects of the infectious process; on the one hand, the aspects involved in the host innate immune response and on the other hand, the capacity of this organism to evade the immune system and interact with different cell types. The exploration of S. aureus interactions with the immune response of bovine mammary gland will help identify targets to outline new preventive or curative alternatives for intramammary infections caused by this organism.