Inflammatory characteristics of distinct abdominal adipose tissue depots relate differently to metabolic risk factors for cardiovascular disease: distinct fat depots and vascular risk factors

• Published in: Atherosclerosis Vol. 239; no. 2; p. 419
• Main Authors: Kranendonk, Mariëtte E G, van Herwaarden, Joost A, Stupkova, Tereza, de Jager, Wilco, Vink, Aryan, Moll, Frans L, Kalkhoven, Eric, Visseren, Frank L J
• Format: Journal Article
• Language: English
• Published: Ireland 01.04.2015
• Subjects: Abdominal Fat - pathology; Adipocytes - cytology; Adipokines - metabolism; Adipose Tissue - pathology; Adipose Tissue - physiopathology; Aged; Anthropometry; Biopsy; Cardiovascular Diseases - blood; Diabetes Mellitus, Type 2 - physiopathology; Female; Humans; Immunohistochemistry; Inflammation - physiopathology; Insulin Resistance; Male; Metabolic Syndrome - metabolism; Middle Aged; Risk Factors; Abdominal fat; Adipose tissue; Subcutaneous; Omental; Insulin resistance; Periaortic; Adipokines; Metabolic syndrome; Mesenteric; Crown-like structures

Abdominal obesity is associated with insulin resistance and metabolic syndrome. However, specific contributions of distinct adipose tissue (AT) depots to metabolic complications of obesity are still unclear. In this study, the inflammatory profile of four distinct abdominal AT-depots and the relatio...