Intracoronary Cardiosphere-Derived Cells After Myocardial Infarction: Evidence of Therapeutic Regeneration in the Final 1-Year Results of the CADUCEUS Trial (CArdiosphere-Derived aUtologous stem CElls to reverse ventricUlar dySfunction) - MALLIARAS, Konstantinos; MAKKAR, Raj R; GERSTENBLITH, Gary; SCHULERI, Karl H; LARDO, Albert C; MARBAN, Eduardo; SMITH, Rachel R; KE CHENG; WU, Edwin; BONOW, Robert O; MARBAN, Linda; MENDIZABAL, Adam; et al. (Journal of the American College of Cardiology, 2014)
Keywords: Aged; Biological and medical sciences; Biopsy; Cardiology. Vascular system; Coronary heart disease; Coronary Vessels; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Heart; Heart Ventricles - pathology; Heart Ventricles - physiopathology; Humans; Injections, Intra-Arterial; Magnetic Resonance Imaging, Cine; Male; Medical sciences; Middle Aged; Myocardial Infarction - complications; Myocardial Infarction - physiopathology; Myocardial Infarction - surgery; Myocarditis. Cardiomyopathies; Myocytes, Cardiac - cytology; Myocytes, Cardiac - transplantation; Recovery of Function; Stem Cell Transplantation - methods; Time Factors; Transplantation, Autologous; Treatment Outcome; Ventricular Dysfunction, Left - etiology; Ventricular Dysfunction, Left - physiopathology; Ventricular Dysfunction, Left - surgery; Ventricular Function, Left - physiology; Myocardial infarction; Prognosis; Coronary artery; Cardiovascular disease; Coronary heart disease; Myocardial disease; Long term; Regeneration; Autograft; Treatment; Dysfunction; Graft; Clinical trial; Circulatory system; Cardiology; Cell; magnetic resonance imaging; CDC; DSMB; ejection fraction; MRI; myocardial infarction; CK-MB; LVEF; LV; cardiosphere-derived cell; troponin I; Data and Safety Monitoring Board; left ventricular ejection fraction; New York Heart Association; oxygen consumption; EDV; Vo; end-diastolic volume; left ventricular; MI; creatine kinase-myocardial band; implantable cardioverter-defibrillator; NYHA; computed tomography; EF; systolic circumferential strain; Ecc; ESV; end-systolic volume; ICD; cardiosphere-derived cells; TnI; CT; SAE; FWHM; full width at half maximum; serious adverse event(s); myocardial regeneration