Micro-RNA signature of lymphovascular space involvement in type 1 endometrial cancer

• Published in: Histology and histopathology Vol. 32; no. 9; p. 941
• Main Authors: Canlorbe, Geoffroy, Castela, Mathieu, Bendifallah, Sofiane, Wang, Zhe, Lefevre, Marine, Chabbert-Buffet, Nathalie, Aractingi, Selim, DaraÏ, Emile, Méhats, Céline, Ballester, Marcos
• Format: Journal Article
• Language: English
• Published: Spain 01.09.2017
• Subjects: Aged; Carcinoma, Endometrioid - genetics; Carcinoma, Endometrioid - metabolism; Carcinoma, Endometrioid - pathology; Endometrial Neoplasms - genetics; Endometrial Neoplasms - metabolism; Endometrial Neoplasms - pathology; Female; Humans; Lymphatic Metastasis - pathology; Lymphatic System - metabolism; Lymphatic System - pathology; Lymphatic Vessels - metabolism; Lymphatic Vessels - pathology; MicroRNAs - genetics; MicroRNAs - metabolism; Middle Aged; Neoplasm Staging

Lymphovascular space involvement (LVSI) is a major prognostic factor in type 1 endometrial cancer (EC). However, its use has been criticized because of poor subjectivity. MicroRNA signatures have recently been linked to EC pathologic characteristics. The aim of this study was to evaluate whether mic...