The mechanism of action of tofacitinib - an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis - Hodge, Jennifer A; Kawabata, Thomas T; Krishnaswami, Sriram; Clark, James D; Telliez, Jean-Baptiste; Dowty, Martin E; Menon, Sujatha; Lamba, Manisha; Zwillich, Samuel (Clinical and experimental rheumatology, 2016)
Keywords: Arthritis, Rheumatoid - drug therapy; Arthritis, Rheumatoid - immunology; Cytokines - physiology; Humans; Janus Kinases - antagonists & inhibitors; Janus Kinases - physiology; Lymphocyte Subsets - drug effects; Neutrophils - drug effects; Piperidines - pharmacology; Piperidines - therapeutic use; Protein Kinase Inhibitors - pharmacology; Pyrimidines - pharmacology; Pyrimidines - therapeutic use; Pyrroles - pharmacology; Pyrroles - therapeutic use; Signal Transduction - physiology