Seronegative anti-GBM Disease with Coexistent ANCA Positivity

• Published in: Bulletin of the Hospital for Joint Diseases (2013) Vol. 72; no. 4; p. 301
• Main Authors: Ratelle, John T, Franco Palacios, Carlos R, Selby, Michael G, Franco Palacios, Maria, Fidler, Mary E, Casey, Edward T
• Format: Journal Article
• Language: English
• Published: United States 2014
• Subjects: Anti-Glomerular Basement Membrane Disease - complications; Anti-Glomerular Basement Membrane Disease - diagnosis; Anti-Glomerular Basement Membrane Disease - immunology; Antibodies, Antineutrophil Cytoplasmic - immunology; Autoantibodies - immunology; Biopsy; Glomerulonephritis - complications; Glomerulonephritis - diagnosis; Glomerulonephritis - immunology; Humans; Kidney - pathology; Lung Diseases - complications; Lung Diseases - diagnosis; Lung Diseases - immunology; Male; Middle Aged

Anti-glomerular basement membrane disease has been reported to coexist with anti-neutrophil cytoplasmic antibody (ANCA) positive vasculitis. Seronegative anti-GBM disease has been previously described and mostly blamed for the relative insensitivity of earlier serologic assays. A 58-year-old male wa...