Usefulness of HbA1c Measurements by HPLC- and Immuno-Assay for Screening Unstable Hemoglobinopathy

• Published in: Annals of clinical and laboratory science Vol. 53; no. 1; p. 134
• Main Authors: Wakuta, Nao, Matsubayashi, Tadashi, Oba, Keiko, Nakashima, Hiromi, Suzuki, Ken, Okumiya, Toshika, Ishibashi, Midori, Koga, Masafumi
• Format: Journal Article
• Language: English
• Published: United States 01.01.2023
• Subjects: Anemia, Hemolytic, Congenital; Chromatography, High Pressure Liquid - methods; Glycated Hemoglobin; Hemoglobinopathies - diagnosis; Humans; Immunoassay; Unstable hemoglobinopathy; Variant hemoglobinopathy; Hemolytic anemia; HbA1c; Red blood cell membrane disease

Unstable hemoglobinopathy (UH), red blood cell membrane disease (MD), and red blood cell enzymopathy are known as major congenital hemolytic anemias. Specialized examinations are needed for their differential diagnosis. We hypothesized that simultaneous measurements of HbA1c levels using high-perfor...