Surgical management of the breast: breast conservation therapy and mastectomy
The twentieth century has witnessed dramatic changes in the surgical management of breast cancer. Herein we focus on the evolution of breast conservation surgery and current surgical trends of lumpectomy, mastectomy and contralateral prophylactic mastectomy. Margin analysis, specimen localization an...
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Published in | The Surgical clinics of North America Vol. 93; no. 2; p. 411 |
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Main Author | |
Format | Journal Article |
Language | English |
Published |
United States
01.04.2013
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Subjects | |
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Abstract | The twentieth century has witnessed dramatic changes in the surgical management of breast cancer. Herein we focus on the evolution of breast conservation surgery and current surgical trends of lumpectomy, mastectomy and contralateral prophylactic mastectomy. Margin analysis, specimen localization and processing, and the benefits of magnetic resonance imaging remain controversial. Neoadjuvant chemotherapy can offer prognostic information and aid in surgical planning while radiation therapy continues to reduce the risk of local recurrence after breast conserving surgery. Despite these advances, mastectomy remains a popular choice for many women and the use of nipple sparing procedures is increasing. Overall the low rates of local recurrence are attributed to the combination of surgery and targeted adjuvant and radiation therapies. |
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AbstractList | The twentieth century has witnessed dramatic changes in the surgical management of breast cancer. Herein we focus on the evolution of breast conservation surgery and current surgical trends of lumpectomy, mastectomy and contralateral prophylactic mastectomy. Margin analysis, specimen localization and processing, and the benefits of magnetic resonance imaging remain controversial. Neoadjuvant chemotherapy can offer prognostic information and aid in surgical planning while radiation therapy continues to reduce the risk of local recurrence after breast conserving surgery. Despite these advances, mastectomy remains a popular choice for many women and the use of nipple sparing procedures is increasing. Overall the low rates of local recurrence are attributed to the combination of surgery and targeted adjuvant and radiation therapies. |
Author | McLaughlin, Sarah A |
Author_xml | – sequence: 1 givenname: Sarah A surname: McLaughlin fullname: McLaughlin, Sarah A email: Mclaughlin.sarah@mayo.edu organization: Department of Surgery, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA. Mclaughlin.sarah@mayo.edu |
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Copyright | Copyright © 2013 Elsevier Inc. All rights reserved. |
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Snippet | The twentieth century has witnessed dramatic changes in the surgical management of breast cancer. Herein we focus on the evolution of breast conservation... |
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SubjectTerms | Breast Neoplasms - mortality Breast Neoplasms - surgery Breast Neoplasms - therapy Chemotherapy, Adjuvant Female Humans Mastectomy, Radical - methods Mastectomy, Radical - mortality Mastectomy, Radical - trends Mastectomy, Segmental - methods Mastectomy, Segmental - mortality Mastectomy, Segmental - trends Neoadjuvant Therapy Neoplasm Recurrence, Local Patient Selection Radiotherapy, Adjuvant Treatment Outcome |
Title | Surgical management of the breast: breast conservation therapy and mastectomy |
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