Risk factors and mortality among patients with severe muco-cutaneous drug reactions

• Published in: Danish medical journal Vol. 62; no. 8; p. A5122
• Main Authors: Crüger, Anne-Mette Torp, Kaur-Knudsen, Diljit, Zachariae, Claus, Rasmussen, Henrik Berg, Thomsen, Simon Francis
• Format: Journal Article
• Language: English
• Published: Denmark 01.08.2015
• Subjects: Adult; Allopurinol - adverse effects; Anti-Bacterial Agents - adverse effects; Antimetabolites - adverse effects; Denmark; Erythema Multiforme - chemically induced; Erythema Multiforme - mortality; Erythema Multiforme - virology; Female; Herpes Simplex - complications; Humans; Male; Middle Aged; Pneumonia, Mycoplasma - complications; Proportional Hazards Models; Retrospective Studies; Risk Factors; Stevens-Johnson Syndrome - etiology; Stevens-Johnson Syndrome - mortality; Denmark

The aim of this study was to examine risk factors and mortality among patients with erythema multiforme (EM), Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). This was a retrospective evaluation of the med-ical records of 250 patients from two Danish tertiary dermatological depar...