CircRNA_0048211 protects postmenopausal osteoporosis through targeting miRNA-93-5p to regulate BMP2

• Published in: European review for medical and pharmacological sciences Vol. 24; no. 7; p. 3459
• Main Authors: Qiao, L, Li, C-G, Liu, D
• Format: Journal Article
• Language: English
• Published: Italy 01.04.2020
• Subjects: Bone Morphogenetic Protein 2 - genetics; Bone Morphogenetic Protein 2 - metabolism; Cells, Cultured; Female; Humans; MicroRNAs - genetics; MicroRNAs - metabolism; Osteoporosis, Postmenopausal - metabolism; RNA, Circular - genetics; RNA, Circular - metabolism

The purpose of this study was to elucidate the potential influence of circular RNA (circRNA)_0048211/miRNA-93-5p/BMP2 regulatory loop in the progression of postmenopausal osteoporosis (PMOP). Bone marrow samples were collected from PMOP patients (n=30) and healthy subjects (n=30) for isolating hBMSC...