Computer-assisted reading of DNA sequences

• Published in: Methods in molecular medicine Vol. 141; p. 177
• Main Authors: Le, Huong, Hinchcliffe, Marcus, Yu, Bing, Trent, Ronald J A
• Format: Journal Article
• Language: English
• Published: United States 2008
• Subjects: Algorithms; Automatic Data Processing - methods; Databases, Genetic; DNA Mutational Analysis - methods; Globins - genetics; Humans; Polymorphism, Single Nucleotide; Quality Control; Sequence Analysis, DNA - methods; Software; Thalassemia - genetics

DNA sequencing is increasingly used in a range of medical activities involving DNA diagnostics and research. This is the result of improving technology and cheaper costs. Paradoxically, a greater demand for DNA sequencing has placed additional work on the laboratory because sequencing profiles must...