Early onset steroid-dependent ulcerative colitis is a predictor of azathioprine response: a longitudinal 12-month follow-up study

• Published in: Medical science monitor Vol. 16; no. 2; pp. PI1 - PI6
• Main Authors: Chebli, Liliana Andrade, Felga, Guilherme Goncalves Eduardo, Chaves, Leonardo Duque de Miranda, Pimentel, Felipe Ferreira, Guerra, Dolores Martins, Gaburri, Pedro Duarte, Zanini, Alexandre, Chebli, Julio Maria Fonseca
• Format: Journal Article
• Language: English
• Published: United States 01.02.2010
• Subjects: Adolescent; Adrenal Cortex Hormones - therapeutic use; Adult; Age of Onset; Azathioprine - adverse effects; Azathioprine - therapeutic use; Colitis, Ulcerative - drug therapy; Colitis, Ulcerative - epidemiology; Demography; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Longitudinal Studies; Male; Middle Aged; Time Factors; Treatment Outcome; Young Adult

Studies assessing the efficacy of azathioprine (AZA) in steroid-dependent ulcerative colitis (UC) are scarce. The aim of this study was to assess the long-term efficacy and safety of AZA in patients with steroid-dependent UC, as well as factors associated with sustained response. In this prospective...