Study on the simultaneous spectrophotometric determination of three components including deoxyschizandrin by ridge regression method

• Published in: Guang pu xue yu guang pu fen xi Vol. 24; no. 10; p. 1238
• Main Authors: Zhang, Li-qing, Li, Ping, Mu, Jie, Zhu, Xian-liang, Li, Ju-qing
• Format: Journal Article
• Language: Chinese
• Published: China 01.10.2004
• Subjects: Cyclooctanes - chemistry; Lignans - chemistry; Polycyclic Compounds - chemistry; Regression Analysis; Spectrophotometry - methods
• ISSN: 1000-0593

Ridge Regression (RR) spectrophotometry was used in the present paper to analyse three components: deoxyschizandin, schisandrin, and gamma-schisandrin. The basic principle and the analytical steps of the approach are described in detail. The computer program of RR is based on VB language. The experimental results show that the RR method has no systematical error as compared to classical method, and the average recovery of each component is all in the range of 92.35% to 108.69%. High accuracy of RR method was obtained. Each component was determined with satisfactory results without any pre-separation. As compared with conventional methods, this method is simple, rapid and suitable for the computer-aided analysis. It was developed in statistical literature to treat these ill-conditioned systems and is an useful analytical method.