Direct and cost-efficient hyperpolarization of long-lived nuclear spin states on universal 15N2-diazirine molecular tags

• Published in: Science advances Vol. 2; no. 3
• Main Authors: Theis, Thomas, Ortiz, Gerardo X., Logan, Angus W. J., Claytor, Kevin E., Feng, Yesu, Huhn, William P., Blum, Volker, Malcolmson, Steven J., Chekmenev, Eduard Y., Wang, Qiu, Warren, Warren S.
• Format: Journal Article
• Language: English
• Published: American Association for the Advancement of Science 01.03.2016
• Subjects: Physics; SciAdv r-articles

More than 10,000-fold enhanced magnetic resonance signals with >20-min signal lifetimes on universal biomolecular markers. Conventional magnetic resonance (MR) faces serious sensitivity limitations which can be overcome by hyperpolarization methods, but the most common method (dynamic nuclear pol...