HPLC method for identification and quantification of benzimidazole derivatives in antiparasitic drugs

• Published in: Acta Poloniae pharmaceutica Vol. 68; no. 6; p. 823
• Main Authors: Kulik, Anna, Białecka, Wanda, Podolska, Marzena, Kwiatkowska-Puchniarz, Barbara, Mazurek, Aleksander
• Format: Journal Article
• Language: English
• Published: Poland 01.11.2011
• Subjects: Albendazole - analysis; Antiparkinson Agents - analysis; Benzimidazoles - analysis; Buffers; Calibration; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid - standards; Fenbendazole - analysis; Hydrogen-Ion Concentration; Mebendazole - analysis; Reference Standards; Reproducibility of Results; Solvents - chemistry

The subject of the study was to develop a versatile HPLC system for identification and determination of four benzimidazole derivatives in the antiparasitic drugs. The tests covered: Zentel, Panacur, Vermox tablets and Systamex suspension. A satisfactory separation was obtained using the Nucleosil C8...