Analysis of information flows in interaction networks: implication for drug discovery and pharmacological research

• Published in: Discovery medicine Vol. 11; no. 57; p. 133
• Main Authors: Fliri, Anton F, Loging, William T, Volkmann, Robert A
• Format: Journal Article
• Language: English
• Published: United States 01.02.2011
• Subjects: Biomedical Research; Clinical Pharmacy Information Systems; Disease; Drug Discovery; Humans; Information Services; Pharmaceutical Preparations

Frequent failures of experimental medicines in clinical trials question current concepts for predicting drug-effects in the human body. Improving the probability for success in drug discovery requires a better understanding of cause-effect relationships at the organism, organ, tissue, cellular, and...