The monitoring role of otoacoustic emissions and oxidative stress markers in the protective effects of antioxidant administration in noise-exposed subjects: a pilot study

• Published in: Medical science monitor Vol. 15; no. 11; pp. PR1 - PR8
• Main Authors: Fetoni, Anna Rita, Garzaro, Massimiliano, Ralli, Massimo, Landolfo, Vincenzo, Sensini, Matteo, Pecorari, Giancarlo, Mordente, Alvaro, Paludetti, Gaetano, Giordano, Carlo
• Format: Journal Article
• Language: English
• Published: United States 01.11.2009
• Subjects: Administration, Oral; Adult; Antioxidants - administration & dosage; Antioxidants - pharmacology; Audiometry, Pure-Tone; Biomarkers - blood; Humans; Inflammation - blood; Male; Monitoring, Physiologic; Noise - adverse effects; Otoacoustic Emissions, Spontaneous - physiology; Oxidative Stress - drug effects; Pilot Projects; Placebos; Protective Agents - pharmacology; Time Factors

Oxidative stress has been recently identified as the pivotal pathway of cochlear damage. The aims of this study were to evaluate whether distortion product otoacoustic emissions (DPOAEs) can discriminate normal subjects with a risk of damage induced by sound exposure, the effectiveness of OAEs in mo...