Independent association between 1,25-dihydroxyvitamin D, 25-hydroxyvitamin D and the renin-angiotensin system: The Ludwigshafen Risk and Cardiovascular Health (LURIC) study

• Published in: Clinica chimica acta Vol. 411; no. 17-18; p. 1354
• Main Authors: Tomaschitz, Andreas, Pilz, Stefan, Ritz, Eberhard, Grammer, Tanja, Drechsler, Christiane, Boehm, Bernhard O, März, Winfried
• Format: Journal Article
• Language: English
• Published: Netherlands 06.09.2010
• Subjects: Aged; Analysis of Variance; Female; Humans; Male; Middle Aged; Prospective Studies; Renin-Angiotensin System; Risk Factors; Vitamin D - analogs & derivatives; Vitamin D - blood

Antihypertensive and tissue-protective properties of vitamin D metabolites are increasingly attributed to the inhibition of renin synthesis by 1,25-dihydroxyvitamin D [1,25(OH)2D] in the kidney. We aimed to document a potential association between 25-hydroxyvitamin D [25(OH)D], 1,25(OH)2D and the ci...